News

Even though 60 percent of Parkinson’s Disease patients develop psychotic symptoms, it was only in 2016 that a treatment for the condition was approved. Nuplazid (pimavanserin) employs an entirely different mechanism to control psychotic symptoms compared to the bulk of antipsychotic medications on the market. The review, “…

Deep brain stimulation (DBS) may help extend the survival of patients with Parkinson’s disease, according to a new study by researchers at the Edward Hines, Jr. VA Hospital in Hines, Illinois. “Overall, DBS surgery has been viewed quite positively by both patients and providers,” Dr. Frances Weaver, the study’s…

Deep brain stimulation (DBS) may be safe for Parkinson’s disease patients who have dementia, according to a small clinical trial by University College London scientists. The study, “Bilateral Deep Brain Stimulation of the Nucleus Basalis of Meynert for Parkinson Disease Dementia — A Randomized Clinical Trial,” was published…

Dutch researchers have developed laser shoes to help Parkinson’s patients overcome a brain disconnect that causes them to stop walking when they want to keep going. Lasers attached to each shoe give patients a visual cue of where they need to go. Without a visual cue, the brain disconnect often leads…

Denali Therapeutics says its experimental therapy for Parkinson’s disease, DNL201 — a small-molecule inhibitor of leucine-rich repeat kinase 2 (LRRK2) — stopped an average 90 percent of LRRK2 kinase activity at its highest concentration. When the drug’s levels dropped to the lowest concentration (known as trough levels), it still inhibited…

Throughout the past year, Parkinson’s News Today has brought you news on Parkinson’s disease treatment development, clinical trials, research, and events. As we look forward to bringing you more news in 2018, we would like to sum up 2017 by bringing you the Top 10 Parkinson’s disease stories that…

Fear is real. Those who live with a chronic illness may deal with it on a daily basis. It robs you of the joy of in your journey, the thrill of tomorrow, the delight of your day. It steals your contentment, empties you of enjoying the now, replaces wonder with…

An implanted wireless device that is smaller than a cubic millimeter may be the future for deep brain stimulation in Parkinson’s disease. A team of engineers at the non-profit Draper Laboratory built such a device, then tested it in animals to prove that it works. Draper’s team and collaborators at…

Niclosamide, an oral medication widely used to eradicate tapeworm infections, may have the potential to slow disease progression in Parkinson’s patients with mutations in the PINK1 gene, researchers report. Their study, “The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson’s Disease Associated Protein Kinase PINK1,” was…

Researchers at the University of California found that tau and beta-amyloid protein deposits in the brains of Parkinson’s patients does not influence their cognitive function. They found, interestingly, that those with greater tau accumulation had higher levels of β-amyloid in the brain. The study, “Associations Between Tau,…