A new technique to isolate specific brain cells, used in a Parkinson’s mouse model, has revealed that genes involved in sensing and using oxygen grow more active in a specific type of nerve cells (neurons) in response to dopamine depletion. Loss of dopamine in the brain is a hallmark…
News
An upgrade to the American Parkinson Disease Association (APDA) Symptom Tracker App, available to patients and caregivers at no cost, includes improvements to make for an easier and more detailed user experience and a Spanish language version. The mobile app, first released last year, was developed to help people…
Caraway Therapeutics has been awarded a research grant from The Michael J. Fox Foundation to further investigate a lysosomal ion channel that could be key in developing a new class of therapeutics for Parkinson’s disease. “Receiving this grant from The Michael J. Fox Foundation is extremely validating for…
The U.S. Patent and Trademark Office (USPTO) has issued a patent covering the intellectual rights to Alterity Therapeutics’ next-generation compounds to treat several neurodegenerative disorders, including Parkinson’s disease. “This broad patent establishes an excellent foundation for the company to pursue multiple therapeutics across a…
Mutations in the gene TNEM4, previously associated with essential tremor, may also be a cause of Parkinson’s disease, at least in its early onset form, a study reported. However, this finding is only suggestive of a link and further research is necessary, its scientists said. The study, “…
Of the roughly 1 million U.S. residents with Parkinson’s disease, some 110,000 are veterans. To improve this population’s health, well-being, and quality of life, the U.S. Department of Veterans Affairs (VA) has formed a partnership with the Parkinson’s Foundation. The intent of the collaboration is to…
The Parkinson’s Progression Markers Initiative (PPMI), a study sponsored by The Michael J. Fox Foundation, is expanding to recruit more participants, the Foundation announced. Currently, the study (NCT04477785) is recruiting new participants — both with and without Parkinson’s disease — at Banner Research Institute in…
Mood problems have a greater impact on quality of life among Parkinson’s patients who have had the neurodegenerative disorder for a long time, compared with those who are earlier in their disease course, new findings show. The results were published in the International Journal of Geriatric Psychiatry, in the study, “Mood…
Networks of mitochondrial interactions in nerve cells may be used as a biomarker in diagnosing Parkinson’s disease, a recent study has shown. The study, “Mitochondria interaction networks show altered topological patterns in Parkinson’s disease,” was published in the journal Nature Systems Biology and Applications. Mitochondria are small organelles…
People with Parkinson’s disease who have higher levels of the protein kininogen-1 in the fluid surrounding their brains and spinal cord are more likely to experience early cognitive impairment, a new study suggests. The study, “Cerebrospinal Fluid Levels of Kininogen‐1 Indicate Early Cognitive Impairment in Parkinson’s Disease,”…
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