Dysphagia, or swallowing difficulties, is associated with a higher risk of death among people with advanced Parkinson’s disease who are treated with Duodopa/Duopa, a levodopa/carbidopa intestinal gel (LCIG), a study shows. Notably, “dysphagia was the only significant predictor of death in our cohort [group], confirming and highlighting the…
Athira Pharma is completing its Phase 2 clinical trial of the experimental therapy fosgonimeton in people with Parkinson’s disease dementia or dementia with Lewy bodies with fewer participants than its initial target enrollment. According to a recent corporate update, the company has closed recruitment with 28 of…
Olatec Therapeutics has been awarded a grant from the Michael J. Fox Foundation for Parkinson’s Research (MJFF) to further investigate its lead oral candidate, dapansutrile, in animal models of Parkinson’s disease. Such preclinical work will be conducted in collaboration with researchers at the Medical University of Innsbruck in Austria…
People with Parkinson’s disease are at a higher risk of simultaneous autoimmune diseases where the immune system erroneously attacks the body, according to a review study. Pooled data from multiple studies showed a significantly increased risk of Parkinson’s combined with either bullous pemphigoid, a rare skin condition, inflammatory bowel…
Medicines for Parkinson’s disease in patients with persistent intolerable abdominal pain showed short and limited usefulness in treating this debilitating non-motor symptom, a study in Japan reported. Nonetheless, researchers found that Duodopa/Duopa,…
IRLAB Therapeutics has selected a dopamine receptor agonist candidate called IRL1117 to advance as a Parkinson’s disease treatment, potentially as a longer-lasting alternative to levodopa with lesser side effects. IRL1117 is designed to be a once-daily oral therapy for the hallmark symptoms of Parkinson’s — tremors, rigidity, and slowness of…
Lower blood levels of total cholesterol and low-density lipoprotein cholesterol (LDL-C), or “bad” cholesterol, are significantly associated with a higher risk of Parkinson’s disease, according to a study from South Korea. In contrast, higher blood levels of high-density lipoprotein cholesterol (HDL-C), or “good” cholesterol, were linked to a lower…
Get regular updates to your inbox.