ANVS401, an investigational therapy for neurodegenerative diseases being developed by Annovis Bio, improved the speed and coordination of people with Parkinson’s disease in a Phase 2a clinical trial, an interim analysis suggests. “The results from this interim analysis are very encouraging. This brings us one step closer to…
Newron Pharmaceuticals and Zambon Pharma agreed to jointly support a potentially pivotal clinical trial of Xadago (safinamide) as a treatment of levodopa-induced dyskinesia in people with Parkinson’s disease. Under the terms of the agreement, Newron and Zambon will evenly share the cost of the intended study. Newron, which developed…
People with Parkinson’s disease have substantial changes in the bacteria living in their gut relative to people without this neurodegenerative disorder, an analysis underscores. “This dysbiosis [microbial imbalance] might result in a pro-inflammatory status which could be linked to the recurrent gastrointestinal symptoms affecting PD [Parkinson’s disease] patients,” its…
An international team of experts has recommended that people with Parkinson’s disease and their caregivers receive vaccines for COVID-19. The recommendations were published in the Journal of Parkinson’s Disease, in a paper titled, “COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the…
People with Parkinson’s disease experience more stress than those without this disease, and high stress levels associate with a worsening of symptoms, research based on a patient survey reported. Mindfulness, a practice of maintaining a heightened state of awareness of thoughts and feelings, may help to lower stress…
PS128, a probiotic sold by Bened Biomedical, eased symptoms of Parkinson’s disease as an add-on treatment to 25 patients in a pilot clinical study, the company announced. Probiotics are live microorganisms that, when consumed, are thought to improve overall health. PS128 is a strain of the bacterial species Lactobacillus…
Neupro patches (rotigotine) — a transdermal form of dopamine treatment — are known to help ease motor symptoms of Parkinson’s disease, and their use can also help with several its non-motor symptoms, researchers report. Their paper, “Rotigotine Transdermal Patch for Motor and Non-motor Parkinson’s Disease: A Review of…
Some medications currently used to treat enlarged prostate, such as alpha-1 adrenergic receptor antagonists — called alpha-blockers — might lower the risk of Parkinson’s disease, according to a new study. While more research is needed to fully determine a causal effect of alpha-blockers in treating the neurodegenerative disease, scientists…
Due to negative clinical trial findings, Biogen has discontinued the development of cinpanemab (BIIB054), an investigational medication intended to treat Parkinson’s disease, the company announced in its 2020 investors report. Cinpanemab is a human-derived antibody that targets alpha-synuclein, thought to be one of the key hallmarks of Parkinson’s disease. In the…
New guidelines published by The British Psychological Society highlight the lack of mental health research and services for people living with Parkinson’s disease and other neurodegenerative conditions, and offers evidence-based recommendations for health professionals to help better serve patients. “We hope that our guidelines will add to…
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