Stem cell capsules restore motor function in Parkinson’s rats
Neural microtissues derived from pluripotent stem cells (iPSCs) can replace dopaminergic neurons, the nerve cells that are lost in…
Articles by Margarida Maia, PhD
Alpha-synuclein fibrils may need inflammation to form Lewy bodies
Both a misfolded form of the alpha-synuclein protein and an inflammatory cue are needed to trigger the Lewy bodies that…
CAP-003 may restore GCase activity above effective levels
A single dose of CAP-003, a gene therapy being developed by Capsida Biotherapeutic, significantly increased the levels of GCase…
Watch app StrivePD helps patients between doctor visits in pilot
App-based consumer technology like Rune Labs’ StrivePD may help people with Parkinson’s disease feel more confident in managing…
Air pollution linked to higher risk of Parkinson’s, dyskinesia in study
Exposure to air pollutants, such as fine particulate matter and nitrogen dioxide, may increase the risk of developing Parkinson’s…
Parkinson’s therapy safely increases GCase activity in healthy volunteers
GT-02287, a potential therapy for Parkinson’s disease, showed promising results in a Phase 1 clinical trial involving healthy volunteers,…
Parkinson’s therapy Bemdaneprocel shows benefits up to 2 years
Patients treated with bemdaneprocel, a cell therapy that Bluerock Therapeutics is developing for Parkinson’s disease, continue to spend…
Pramipexole side effects linked to overactive brain region in study
Pramipexole, the active ingredient in the Parkinson’s disease therapy Mirapex, appears to overactivate a brain region known as…
Parkin protein tied to Parkinson’s disease aids anti-tumor responses
Parkin, a protein linked to Parkinson’s disease that’s lost in certain types of cancer, triggers the release of signaling…
Regular exercise, even if moderate, helps ease motor symptoms: Study
Ten consecutive weeks of either high-intensity interval training or continuous training, which is moderate in intensity, effectively eased disease…