PNA5 targets Parkinson’s cognitive symptoms, may slow decline
Mice modeling Parkinson’s disease performed better on tests of memory and spatial recognition when given daily under-the-skin injections of…
Articles by Margarida Maia, PhD
Phase 2 trial of therapy for LRRK2-linked Parkinson’s may open soon
An upcoming Phase 2 clinical trial is due to test NEU-411, a brain-penetrant oral small molecule that Neuron23…
Parkinson’s Foundation details essential steps to better hospital care
People with Parkinson’s face risks during hospital stays, even when admitted for reasons other than the neurodegenerative disease itself,…
Crushed dried seeds of Chinese date ease Parkinson’s in mouse model
Crushed dried seeds of the jujube fruit, a traditional herbal medicine also known as Chinese or red date, eased the…
Vesalius, GSK partner to develop new Parkinson’s treatments
Vesalius Therapeutics has entered into an agreement with GSK to advance the development of new therapies for Parkinson’s…
RNA scaffold drives alpha-synuclein protein clumping in neurons
A type of RNA structure called G-quadruplex, or G4 — a four-stranded RNA structure that forms when calcium enters cells…
Brain pathways add layer to movement regulation: Mouse study
Two newly identified brain pathways originating from the striosome — a cluster of nerve cells (neurons) in the striatum, a…
Dopamine’s rapid release key for motivation, less so for movement
A rapid release of the chemical messenger dopamine in the brain is not needed for initiating movement, while it’s important…
Fatigue most common Parkinson’s symptom reported by app users
Fatigue is the most common complaint among people with Parkinson’s disease, according to anecdotal data from a free app…
Some probiotics have potential as add-on treatment for Parkinson’s
Researchers have identified six probiotics — live bacteria usually used as dietary supplements to help with digestion — with the…