Introns in DNA, Largely Ignored, May Be Parkinson Determinants
Researchers have identified distinct changes to introns — a historically understudied component of genes — associated with the presence and…
Articles by Lindsey Shapiro, PhD
Poor Sleep Seems to Worsen Parkinson’s Symptoms
Poor quality of sleep is linked to worse motor and nonmotor symptoms in people with Parkinson’s disease, a study…
Depression, Anxiety Meds Tied to Disease Risk in Older Women
The use of antidepressants or anti-anxiety medications was linked to the development of Parkinson’s disease in women 65 and…
Strength Training Fails to Improve Orthostatic Hypotension in Pilot Study
Eight weeks of leg strength training failed to prevent sudden drops in blood pressure upon standing, a condition called orthostatic…
Dysfunction Of Lysosome Protein TMEM175 Could Be Risk Factor
A protein called TMEM175 is critically important for maintaining the proper acidity of lysosomes — cellular compartments that clear waste…
Changes in Brain Architecture Tied To Poor Bimanual Coordination
Small-scale, or microstructural, brain alterations observed on the MRIs of people with Parkinson’s disease were associated with worse bimanual…
App for Voice ‘Games’ May Aid At-home Speech Therapy Practice
Researchers have proposed a set of voice exercise games to help speech quality in people with Parkinson’s disease, which…
Trial of Fibroblast Growth Factor-1 Shows Safety, Suggests Efficacy
A first study in patients of an intranasal-delivered therapy for Parkinson’s disease is now complete, and early findings support…
New Role for Alpha-synuclein Uncovered by Researchers
The buildup of alpha-synuclein in cells and brain tissue in Parkinson’s disease patients is linked to the disruption of…
Trial to Test Wearable ‘Exoskeleton’ as Training Aid for Gait Problems
A clinical trial will evaluate how well a wearable “exoskeleton” device aids rehabilitation training to improve walking mechanics and neuromuscular function in…