A two-year, global, observational study that will assess the contribution of genetic factors in the development of Parkinson’s disease has been launched by Centogene, in collaboration with the University of Lübeck. The new study (NCT03866603), which is called “Rostock International Parkinson’s Disease Study” or…
A new test can analyze cerebrospinal fluid samples and help measure how many toxic aggregates of alpha-synuclein can be found in the brains of patients with Parkinson’s disease. The new assessment strategy was developed by Japanese researchers and was reported in a study, “Ultrasonication-based rapid amplification of…
Lack of tissue oxygenation associated with episodes of upper airway obstruction in patients with obstructive sleep apnea syndrome (OSAS) may increase the levels of alpha-synuclein in the blood and may contribute to the development of Parkinson’s disease, a study says. The study, “Plasma α‐synuclein levels are increased…
Alpha-synuclein reduces the levels and impairs the function of ATP-dependent Clp protease (ClpP), an enzyme found in mitochondria — the cell compartments responsible for the production of energy — causing mitochondrial damage and oxidative stress, a study shows. The study, “Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative…
In Parkinson’s disease patients, fatigue is linked to specific patterns of brain degeneration that are not present in individuals of the same age who do not have the condition, a study reports. Findings of the study, “Structural brain correlates of fatigue in older adults with and without Parkinson’s…
The ability to block out irrelevant information when asked to recognize and name objects, known as inhibitory processing, remains intact in patients with Parkinson’s disease, a study has found. The study, “The Suppression of Irrelevant Semantic Representations in Parkinson’s Disease,” was published in the journal Frontiers in Human…
Cancer patients appear to have a lower risk of developing Parkinson’s disease, even when taking into account important risk factors and overall survival, a study has found. The study, “Cancers Preceding Parkinson’s Disease after Adjustment for Bias in a Danish Population-Based Case-Control Study,” was published in Neuroepidimiology.
A new approach to deep brain stimulation (DBS) was able to reduce both motor and cognitive impairments in a patient with Parkinson’s disease, a case study reports. Described by the researchers in Spain who conducted the study, this alternative to conventional DBS involves a single electrode that is placed…
Patients with Parkinson’s disease and their caregivers are usually active and ready to adopt strategies to improve their quality of life and disease management, but lack self-management support, a study finds. The study, “Development of the Integrated Parkinson’s Care Network (IPCN): using co-design to plan collaborative care for…
Supplements of omega-3 fatty acids and vitamin E may help control genes involved in brain inflammation and body metabolism in patients with Parkinson’s disease, a study has found. The study, “The effects of omega-3 fatty acids and vitamin E co-supplementation on gene expression related to inflammation, insulin…
Get regular updates to your inbox.