UB-312, an experimental vaccine being developed for Parkinson’s disease by Vaxxinity, induced the production of antibodies targeting alpha-synuclein and slowed protein clumping in patients’ cerebrospinal fluid (CSF), the fluid that surrounds the brain and the spinal cord. The vaccine is designed to stimulate a patient’s immune system…
Biopas Laboratories has asked the regulatory agencies of six countries in Latin America to approve Inbrija for Parkinson’s disease off periods, according to Acorda Therapeutics, the therapy’s developer and Biopas’ partner. Inbrija is a self-administered, inhaled levodopa therapy developed to reduce periods when motor symptoms are…
Chick-fil-A Dawg Bowl 2023, hosted by former Bulldogs football coach Mark Richt, has raised more than $758,000 to support research on Parkinson’s disease at the University of Georgia (UGA). Launched by a $500,000 donation from the Richt Family Foundation, all the proceeds will go to UGA’s Isakson…
A first healthy volunteer has been dosed in a Phase 1 clinical trial assessing the safety and tolerability of HL192, an investigational therapy for Parkinson’s disease. The treatment, given orally, is designed to activate Nurr1, a key protein that regulates the development and maintenance of dopaminergic neurons. These nerve…
The American Parkinson’s Disease Association (APDA) received three MM+M awards, including the titanium Best in Show, for its ParkinSex guide to help people with Parkinson’s disease and their partners retain sexual intimacy. Now in its 20th year, the MM+M Awards recognize creativity and effectiveness in…
A five-year project funded by a $5 million National Institutes of Health (NIH) research grant will study how the brain regulates movements, by allowing people with Parkinson’s disease to play video games during brain surgeries. The goal, according to researchers, is to obtain information that can be applied to…
Stem Pharm and Verge Genomics are teaming up to develop a 3D brain model of Parkinson’s disease that uses advanced computational tools to validate new therapeutic candidates. The collaboration will leverage Stem Pharm’s human-derived “mini-brains” that model inflammation of the brain — neuroimmune organoids — and Verge’s…
A neuroscientist at Northwestern University in Chicago was given the 2023 Annemarie Opprecht Parkinson Award, an international honor recognizing significant contributions to Parkinson’s disease research. James Surmeier, PhD, is a professor and chair of university’s neuroscience department, and a scientific advisor to the Michael J. Fox…
The mutated form of alpha-synuclein protein — a key player in the development of Parkinson’s disease — can travel in the brain to various regions using the brain’s immune system before it builds up into toxic clumps, or aggregates, a new study has found.
Homogenous cell therapy — treatments using only one cell type — may ease disease severity, lessen motor symptoms, and improve activities of daily living in people with Parkinson’s disease, according to a new systematic review. These effects were observed during patients’ off periods, times when the medication wears off…
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