Probiotic could ease Parkinson’s symptomsPosted by ally on March 9, 2021 at 8:08 pm
Have you heard of PS128? It’s a probiotic which, according to a small study, may ease symptoms of Parkinson’s disease when used as an add-on treatment. You can learn more about it by listening to this flash briefing.
What do you think of this news? Have you tried or will you try PS128? If you’ve tried it, have you seen any results?
MemberMarch 11, 2021 at 3:13 pm
After reading the study I decided to order Solace which contains PS128. Just started it a few days ago so it’s too early to notice any effect. I didn’t have any negative effect so that is good.
ModeratorMarch 11, 2021 at 7:00 pm
Hi Denise, I hope you’ll keep us updated if you notice anything! 🙂
MemberSeptember 3, 2021 at 6:47 pm
Hi Denise – any update on symptoms reduction since you have been taking Solace? Did you take it for three months?
MemberSeptember 13, 2021 at 10:20 am
I listened to Ally’s “flash briefing,” but I cannot find the complete study. Please let me know what it’s listed as and where I might find it. Thanks.
MemberAugust 12, 2021 at 4:58 pm
I have been taking a probiotic VSL3# for a moth now and I think it has helped
MemberSeptember 7, 2021 at 10:03 am
I was diagnosed with Parkinsonism in 2010 and have tried a bunch of things besides the standard medicines. Nicotine patches like they do in France. Coenzyme Q10 like they do in the US.
I have been using Lactobacillus plantarum PS128. Since it is a living culture, you can make your own. So I make “yoghurt” and eat it for breakfast. I eat about 1 cup in the morning, but even though I have been doing it for several months I have to admit I miss some days. I can’t tell if it helps or not–so I will keep making my own, which means I don’t know the potency of what I am getting. I really do believe that the gut and the brain effect each other, so I am not giving up.
One reason I haven’t felt the need to take the PS128 regularly is that for me Mannitol has given me my life back. Just the other day I suddenly realized that my smelling had improved a lot… I had already noticed things like my hands swinging again when walking (I haven’t done that for ten years!); my wife commenting that my Poker-face was significantly better; my handwriting has gotten normal size again and I can actually read what I write! I feel a lot less stiff–so I have dared to go out into the forest to pick bilberries (living in Sweden where we have the right of public access, one can pick wild berried in any forest). I thought that activity was off the books for me since a year ago I tumbled while I picked berries, so I thought I would have to give it up.
I have been taking 1 teaspoon a day of Mannitol for 10 months now. It took awhile for it to work, but even though the experts say there is no cure for Parkinson’s, this sure reduces the symptoms.
Good luck with the PS128!
MemberSeptember 7, 2021 at 7:01 pm
Thanks for posting this study … I will try Solace … the data seems compelling …
Re: Mannitol … After reading a spirited chat forum about it a few months ago (and following it for longer), I started using it … I began with a 1/4 teaspoon and worked my way up to 2 1/2 teaspoons in about three weeks … I based that dose on info I found on an Israeli broadcast news report with the scientists behind the original study …
I believe it is helping to ease my tremor and reduce some of the slowness … I experienced some changes in about two weeks, which continued to show improvements since … I feel a lot more comfortable moving … almost like my old self again … However, I don’t think this will work for everyone … if you try it, be patient …
I am using Bulk Supplements, which I found on Amazon … I’m eager to hear others’ thoughts and experiences on both of these …
MemberSeptember 14, 2021 at 3:20 am
Thank you Charles for sharing about how Mannitol helps you. I just came back from a trip to see a daughter and her family, and I forgot to take my Mannitol along. I was gone five days without the positive effects of Mannitol disappearing. Which tells me there has been some major repair-work in my brain, cleaning out the Lewy body clumps and reversing some of the damage done. I don’t know for sure, but it has clearly been helpful for me.
MemberOctober 25, 2023 at 2:49 pm
It’s my understanding that PS128 specifically is not necessarily present in yogurt in great enough numbers to have an impact. Bened Life makes a capsule that is only PS128, but it is very expensive. I took one month’s supply and have now ordered the 3-month supply. Has anyone else tried it?
MemberOctober 26, 2023 at 2:36 pm
Yes. For my husband. I recently purchased the brand Neuralli, which is L. Plantarum PS128. I did get a first time discount to $130, from retail price around $185 for a 30 day supply with 60 billion CFU’s per 2 pills. It completely reversed his constipation, which he has had for over 3 years. Before I purchased the Neuralli, one month earlier, I bought another brand at a supplement store that only contained 5 billion CFU’s per pill to test it out, and it worked just the same as the higher CFU count.. I thought Neuralli was worth a try since it has 10 times the count of the All-Flora Probiotic which was only $35. It seems he had same results from both and so I’d suggest a person try the less expensive type first as I did if they are on a budget. As long as it has the L. Plantarum pro biotic in sufficient quantities.
MemberOctober 26, 2023 at 5:14 pm
Thank you for posting. What was the brand of the lower expensive one you tried that seem to work? Where did you buy it? I would like to try the one that worked on his constipation issue first.
MemberOctober 26, 2023 at 9:36 pm
PS128 is a specific strain of lactobacillus plantarum. Other strains have not been shown to have the same benefits.
MemberOctober 27, 2023 at 10:25 am
So, I did a little research and it looks like the only one I could find with PS128 was Neuralli. Have you heard of any other brand?
MemberNovember 7, 2023 at 4:27 pm
There are some others that claim to contain it. As far as what any supplement actually contains, I am always skeptical:
MemberOctober 29, 2023 at 9:23 am
The less expensive brand containing l. Plantarum is New Chapter, All-Flora Probiotic. My husband took 1 before bedtime and that was all he needed. There’s no recommended dosage so one could take 2 or 3 capsules before bedtime until they see results. My husband also takes 5 – 300 mg. B-1 or 1500 mg per day, and does red light therapy (photobiomodulation) with a medical grade Coronet twice a day. These 3 therapies, and the levadopa have eliminated 50% of his physical symptoms and as I previously wrote, the L. Plantarum appears to have eliminated constipation issue.
MemberOctober 31, 2023 at 6:09 pm
Yes I have been using Bened Life Neuralli PS128 for about 5 months now. I’ve not really noticed any benefit other than it may have reduced my constipation slightly. It’s very expensive so I am considering reducing the dose or stopping all together to see what happens.
MemberNovember 10, 2023 at 11:04 am
Regarding the discussion on Mannitol. Can someone tell me what specific Parkinson’s symptoms that it targets/improves? I am an RN, retired professionally but “working” full time as my husband’s caregiver – he has Parkinson’s. The only thing I know about Mannitol is when I worked in the ICU (many years ago!) and it was an IV drug to reduce swelling in a patient’s brain.
MemberSeptember 3, 2021 at 6:49 pm
There have been much discussion about Mannitol on these forums. Maybe they can be reposted? My husband has taken for over a year. It has definitely helped but balance benefit seems to be gone. It continues to help masking.
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