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    • #19468
      Mary Beth Skylis
      Moderator

      There’s still a lot of debate about whether or not there is a genetic component that relates to Parkinson’s disease. My Dad (diagnosed in 2013) thinks that his brother may have PD, too. But the rest of our family history (as far as we know) seems free of the disease. This makes me think that the diagnosis could be environmental for both of them. Do or did any of your family members have Parkinsons? Do you think there could be a genetic component?

    • #20291
      John Lefcourte
      Participant

      Yes, my Father did and my Male 1st Cousin had early onset.

    • #20320
      John H
      Participant

      My mother and her father had Parkinson’s. I have many of the same symptoms as of my mother.

      No hand  tremors, walking, gait , freezing, swallowing, hand writing, energy level and a

      sharp mind.

    • #20323
      Daniel Best
      Participant

      My dad had PD onset at 62, me at 59.  It makes me think of him all the time, and how little he complained.

    • #20326
      Charles Schiller
      Participant

      Yup. My maternal grandfather. The role of genetics in PD is, think, uncertain among the scientific but I’m certain there must be a connection.

       

    • #20328
      Jim Browne
      Participant

      Yes, I have a single L444P GBA mutation that gave me a 17% of getting Parkinson’s. Carriers in family have been traced  back 200 years. I was part of the Sanofi clinical trial that was billed as the first trial to use genetics to target a real cure of PD. The trial recently ended in failure with the study drug shown to be ineffective. We have a ways to go with this approach. It is interesting that 83% of the people with this mutation don’t get PD.

    • #20333
      Jeffery Hill
      Participant

      My father developed PD symptoms at the age of 57, and I did at 56.  His first cousin also had PD.  I was tested for known genetic markers but the results apparently were negative.

    • #20343
      Phil Gattis
      Participant

      My mother had Parkinson’s.

    • #20342
      Garrett McAuliffe
      Participant

      I had Parkinson’s at the same age as my father with similar symptoms. As he was, I was diagnosed at 62 years old. And my grandmother his mother also seems to have had Parkinson’s. I’m sure that there’s a genetic link. It’s complicated but I don’t think it’s debated anymore.

    • #20341
      Garrett McAuliffe
      Participant

      I thought I had Parkinson’s at the same age as I was diagnosed 62 years old. And my grandmother his mother also seems to have had Parkinson’s. I’m sure that there’s a genetic link. It’s complicated but I don’t think it’s debated anymore.

    • #20353
      Regina
      Participant

      No one in the family had PD.  Both my mother and I have ET.  My doctor told me that patients with ET have about a 5-6%

      Increased chance of developing PD.

      Also, there is a propensity for those of Irish descent to have ET (eg, Katherine Hepburn).

       

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