Jim Browne

Yes, I have a single L444P GBA mutation that gave me a 17% of getting Parkinson’s. Carriers in family have been traced  back 200 years. I was part of the Sanofi clinical trial that was billed as the first trial to use genetics to target a real cure of PD. The trial recently ended in failure with the study drug shown to be ineffective. We have a…[Read more]

I had an olfactory hallucination where everything smelled like wasabi Japanese mustard. After a couple of weeks it just disappeared.

JimB

Unlike most cases of Parkinson’s, the probable root cause of my PD has been established by numerous scientific studies. I have a GBA mutation with the variation, L444P. This increased my odds of getting PD by 10 to 20 times. In my family there enough present day relatives with PD that I can trace  the mutation back 200 years by…[Read more]

I have a GBA mutation, l444p, that increases my risk of getting PD by 10 times and was heavily  exposed to trichloroethylene, a solvent linked in a few studies to increased PD risk.

I have a GBA mutation L444P. Evidence not discussed in the paper indicates it is one of the most common GBA mutations world wide, if not the most common. 23andme currently doesn’t test for it. I got this result from Genos that was verified by the MJF PPMI initative. It took 2 tries by Indiana U to test for the right variant. I have joined one of…[Read more]