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Jim Browne

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@brownejames

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    Jim Browne replied to the topic Do or did any of your family members have Parkinsons? in the forum Diagnosis​ ​Information​ ​and​ ​General​ ​Questions 1 year, 11 months ago

    Yes, I have a single L444P GBA mutation that gave me a 17% of getting Parkinson’s. Carriers in family have been traced  back 200 years. I was part of the Sanofi clinical trial that was billed as the first trial to use genetics to target a real cure of PD. The trial recently ended in failure with the study drug shown to be ineffective. We have a…[Read more]

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    Jim Browne replied to the topic What is your strangest symptom? in the forum Parkinson's Disease Symptoms 2 years ago

    I had an olfactory hallucination where everything smelled like wasabi Japanese mustard. After a couple of weeks it just disappeared.

    JimB

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    Jim Browne replied to the topic Do you have theories about why you have Parkinsons? in the forum Diagnosis​ ​Information​ ​and​ ​General​ ​Questions 2 years, 3 months ago

    Unlike most cases of Parkinson’s, the probable root cause of my PD has been established by numerous scientific studies. I have a GBA mutation with the variation, L444P. This increased my odds of getting PD by 10 to 20 times. In my family there enough present day relatives with PD that I can trace  the mutation back 200 years by…[Read more]

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    Jim Browne replied to the topic Do you have theories about why you have Parkinsons? in the forum Diagnosis​ ​Information​ ​and​ ​General​ ​Questions 2 years, 4 months ago

    I have a GBA mutation, l444p, that increases my risk of getting PD by 10 times and was heavily  exposed to trichloroethylene, a solvent linked in a few studies to increased PD risk.

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    Jim Browne replied to the topic Genetic Parkinson’s More Common Than Thought, Global Survey Shows in the forum Parkinson’s Research News 2 years, 11 months ago

    I have a GBA mutation L444P. Evidence not discussed in the paper indicates it is one of the most common GBA mutations world wide, if not the most common. 23andme currently doesn’t test for it. I got this result from Genos that was verified by the MJF PPMI initative. It took 2 tries by Indiana U to test for the right variant. I have joined one of…[Read more]

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    Jim Browne became a registered member 2 years, 11 months ago

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This site is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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