Findings from a recent study published in the American Journal of Preventive Medicine revealed an association between increasing hours of television viewing per day and risk of death from its major causes in the United States, including Parkinson’s disease. TV viewing is the most prevalent of leisure-time behaviors…
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University of Dundeen scientists have uncovered the molecular mechanisms and targets under the effect of a specific gene mutation involved in Parkinson’s disease development and which could prove to be strong targets for new therapies and even early disease detection. The paper entitled “Phosphoproteomic screening identifies Rab GTPases as novel downstream targets…
Recent research identified a new technology that can successfully deliver drugs across the blood-brain barrier, conferring neuroprotection in a mouse model of Parkinson’s disease. The study entitled “Heterotopic Mucosal Grafting Enables the Delivery of Therapeutic Neuropeptides Across the Blood Brain Barrier” was published in Neurosurgery…
In a recent paper published in The Lancet Neurology, researchers evaluated the analgesic effect of prolonged-release oxycodone-naloxone (OXN PR) in patients with Parkinson’s disease (PD) suffering from severe and chronic pain in a pioneer Phase II clinical trial. Pain is a very common, non-motory symptom in PD patients (approximately 60% of patients)…
Parkinson’s UK, the largest charity funder of Parkinson’s research in the U.K., recently launched a new research project that explores the possibility of using an individual’s skin odor to diagnose Parkinson’s disease. Watch the video below to learn more about this new project from Parkinson’s UK’s director of research, Arthur Roach:…
A team of researchers localized the specific types of neurons involved in movement, work that might be of relevance to understand neurodegenerative diseases like Parkinson’s and Huntington’s. The study, entitled “Cell-Type-Specific Sensorimotor Processing in Striatal Projection Neurons during Goal-Directed Behavior,” was published in Neuron. Neurodegeneration occurs when…
Researchers at King’s College London have identified a gene, HIFalpha, that plays a role in the regulation of nerve signals from damaged mitochondria that, in turn, affect nerve cell function, and which holds out the possibility of eventually finding a way to turn that gene off and restore function. The…
Researchers at the Georgetown University Medical Center reported nilotinib (Tasigna® by Novartis), a treatment for chronic myelogenous leukemia (CML), successfully treated Parkinson’s disease and Lewy body dementia patients in a Phase I trial. The complete results were presented during the annual meeting of the society of Neuroscience, Neuroscience 2015, held in Chicago…
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Stable Parkinson’s Disease Drug Therapy Status Quo Could Soon Be Disrupted by New Category Entrants
Burlington, Massachusetts-based, medical market research firm Decision Resources Group (DRG) reports, citing analyses of U.S. longitudinal patient-level claims data, that the Parkinson’s disease (PD) drug treatment algorithm remains highly stable, with levodopa (either alone or in combination with carbidopa) as its foundation. Parkinson’s disease (PD) is a…
Valley View, Ohio-based Great Lakes NeuroTechnologies (GLNT) have announced receipt of a new allowance of claims from the U.S. Patent Office focused on technology for Parkinson’s disease (PD) diagnostics and treatment. This particular patent application covers a method of measuring Parkinson’s motor symptoms such as tremor, bradykinesia, and rigidity, and…
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