Phase 1/2 Trial to Test Investigational Therapy RTB101 in Parkinson’s Disease
A new Phase 1/2a clinical trial will investigate resTORbio’s therapy candidate RTB101, alone or in combination with sirolimus,…
Articles by Patricia Inácio, PhD
ProMIS to Present Data on Potential of Antibodies to Target Toxic Alpha-Synuclein in Parkinson’s
ProMIS Neurosciences will present evidence of the selectivity of several of its antibody candidates to target the toxic forms of…
Anavex 2-73 Trial Recruitment Reaches Halfway Mark
A Phase 2 trial evaluating the efficacy and safety of investigational Anavex 2-73 as a treatment for Parkinson’s disease dementia has recruited…
Exercise Improves Cognitive Function in Parkinson’s, Review Finds
Exercise has the potential to improve cognitive function in people with Parkinson’s disease, and has positive effects on motor symptoms,…
AbbVie, Voyager Team Up to Develop Antibodies for Parkinson’s, Other Diseases
AbbVie and Voyager Therapeutics have extended their collaboration to co-develop and commercialize antibodies that target the toxic forms of alpha-synuclein to…
ProMIS Neurosciences Develops Antibodies Targeting Toxic Forms of Alpha-Synuclein
ProMIS Neurosciences has identified several antibody candidates that specifically target the toxic forms of alpha-synuclein, a key component of…
Gene Therapy Preserves Nerve Fibers in Mouse Model of Severe Neurodegeneration
An investigational gene therapy was able to preserve nerve axons — long projections that connect nerve cells and transport information —…
Deep Brain Stimulation May Increase Dementia Risk in Some Parkinson’s Patients, Study Suggests
Parkinson’s disease patients with mild cognitive impairment who undergo deep brain stimulation are at a higher risk of cognitive…
Mutations in Gene Associated With Hereditary Parkinson’s Disease Lead to Toxic Accumulation of Manganese
Researchers have found that mutations in a gene linked to hereditary forms of Parkinson’s disease — SLC30A10 — cause accumulation of toxic…
Gout May Increase Parkinson’s Risk in Older People, Study of US Medicare Data Suggests
Gout appears to be associated with a higher risk of incident Parkinson’s disease in older adults, according to…