New Gene Therapy Delivery Method May Open BRAVE New World in Parkinson’s Research
A new method allows researchers to develop adeno-associated virus (AVV) — commonly used as the vehicle for gene therapies —…
Articles by Patricia Inácio, PhD
3D Structure of Brain Alpha-Synuclein More Heterogeneous Than Previously Thought, New Study Reports
Clumps, or aggregates of alpha-synuclein protein in the brain, a hallmark of Parkinon’s disease, are more heterogeneous than…
First DUB Enzymes Identified by Partnership as Potential Therapeutic Targets for Parkinson’s and Alzheimer’s
Mission Therapeutics and AbbVie have identified several molecules, called deubiquitylating enzymes, or DUBs, that may be potential therapeutic…
Dosing Begins in Phase 2 Trial of CNM-Au8, Potential Therapy for Dopaminergic Neurons
A pilot Phase 2 study evaluating CNM-Au8, an investigational Parkinson’s treatment aiming to protect nerve cells, has started dosing patients,…
RightEye’s Vision System for Early Diagnosis Named ‘Breakthrough Device’ by FDA
RightEye’s Vision System, an advanced eye-tracking device that measures eye tremors to help diagnose Parkinson’s disease…
Sunovion Re-Submits Approval Request for APL-130277 to FDA for Treating Parkinson’s Off Periods
Sunovion Pharmaceuticals has re-submitted a new drug application (NDA) to the U.S. Food and Drug Administration (FDA), once…
Gut Inflammation May Increase Risk for Parkinson’s Disease, Review Study Suggests
Inflammation in the gut, a hallmark of autoimmune disorders such as inflammatory bowel disease, may contribute to an earlier…
Alzheimer’s Treatment Not Seen to Aid Patients’ Balance After 6 Weeks, Small Study Suggests
Treatment with Aricept (donepezil) for six weeks does not seem to improve balance, either while standing or walking,…
Potential Therapy for Dopaminergic Neurons, CNM-Au8, Enter Phase 2 Trial in Parkinson’s Patients
CNM-Au8, an investigational therapy by Clene Nanomedicine, improved the survival of dopaminergic neurons, helped prevent loss of mitochondria,…
Nourianz Now Available in US as Add-on to Carbidopa/Levodopa to Treat Parkinson’s Off Periods
Kyowa Kirin’s Nourianz (istradefylline) tablets are now available in the United States as an add-on treatment for off…