Author Archives: Patricia Inacio PhD

Fat-coated Microbubbles May Aid Parkinson’s Treatment by Getting Past Blood-Brain Barrier

Scientists using fat-coated microbubbles have possibly developed away of carrying therapies for Parkinson’s disease directly to areas of the brain where they are needed, without affecting other organs. The study, “Lipid microbubbles as a vehicle for targeted drug delivery using focused ultrasound-induced blood-brain barrier opening,” was published in the…

Dopamine-Neurons’ High Energy Requirements Leads to Neuronal Overheating in Parkinson’s Disease

In a new study entitled “Elevated mitochondrial bioenergetics and axonal arborization size are key contributors to the vulnerability of dopamine neurons” scientists discovered why dopamine producing neurons are particularly vulnerable in Parkinson’s disease. These new findings point towards a key role for mitochondria and these neurons’ high energy requirements…

Activity of Two Specific Proteins May Result In Parkinson’s Disease

In a new study entitled “VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson’s Disease” scientists discovered that loss of the VPS35 protein expression in Parkinson’s disease interferes…

High Dopamine Levels Boost Risky-Decision Making

In a new study entitled “Dopaminergic Modulation of Decision Making and Subjective Well-Being”, published in the Journal of Neuroscience, researchers show that decisions on risk-taking may be influenced by a boost in the levels of the neurotransmitter dopamine. These findings are in line with previous reports that…

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