Marisa Wexler, MS, senior science writer —

Marisa holds a Master of Science in cellular and molecular pathology from the University of Pittsburgh, where she studied novel genetic drivers of ovarian cancer. Her areas of expertise include cancer biology, immunology, and genetics, and she has worked as a science writing and communications intern for the Genetics Society of America.

Articles by Marisa Wexler

Study Explores Imbalances in Brain That Lead to LID

An imbalance between the signaling molecules dopamine and sonic hedgehog in the brain may be the cause of the movement disorder caused by dopamine-replacing medicines used to treat Parkinson’s disease. That’s according to findings published in Communications Biology, in the study, “Dopaminergic co-transmission with sonic hedgehog…

Small Molecules, STARs Treat Cell Models of GBA1-linked Parkinson’s

Two investigational small molecules known as GT-02287 and GT-02329 lowered toxic protein levels in patient-derived cell models of Parkinson’s disease associated with a mutation in GBA1, their developer, Gain Therapeutics, announced. Gain is planning additional preclinical studies this year that could support applications to regulatory agencies allowing the compounds to…

Variety of Ways to Help Patients With Walking Not Widely Known

People with gait difficulties due to Parkinson’s disease make adjustments that aid in walking, but many are not aware of the variety of “compensation strategies” available to them, a study based on a patient survey reported. Some of these strategies may be more useful in certain situations or to a given…

B-SOiD Algorithm May Make it Easier to Study Behavior

A novel machine learning algorithm called B-SOiD quickly and efficiently analyzes animal behaviors, and may be useful in assessing movement disorders in people with Parkinson’s disease. Researchers described their findings in the study, “B-SOiD, an open-source unsupervised algorithm for identification and fast prediction of behaviors,” published in Nature…

Many Patients Harbor Misconceptions About Vaccines

Many people with Parkinson’s disease have misconceptions about routine vaccinations, with more than one of 10 patients thinking they are not recommended for people with Parkinson’s — even though they very much are, as they can be life-saving. The results, based on a survey of patients in the U.S.,…

Electrical Stimulation of Brain via Scalp May Ease Bradykinesia

Electrical stimulation given through the scalp to a brain region called the supplementary motor area may ease certain aspects of upper limb bradykinesia in people with Parkinson’s disease, a small study suggests. The study, “Transcranial direct current stimulation of supplementary motor area improves upper limb kinematics…

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