Blockade of PAAN Enzyme Improves Motor Function in Mice
Inhibition of a DNA-destroying enzyme called PAAN protected against nerve cell death and lessened motor symptoms in mouse models of…
Articles by Lindsey Shapiro, PhD
Electroconductive Hydrogels Ease Parkinson’s Symptoms In Rat Model
Electroconductive hydrogels prevented the loss of dopamine-producing nerve cells (neurons) and motor function when injected into the brain, a study…
Nanoparticles Restore Mitochondrial Function in Mouse Study
A team of researchers has designed nanoparticles able to restore the function of mitochondria — cells’ energy production centers —…
Nerve Cell Lines Derived From Stem Cells of PPMI Study Donors Created
Fujifilm Cellular Dynamics reported that it has developed, using stem cells from people with Parkinson’s disease, dopaminergic neurons…
Inflammatory Markers, Sleep Disorder Linked In Parkinson’s
Blood levels of c-reactive protein (CRP) and the lymphocyte-to-monocyte ratio (LMR), two indicators of systemic inflammation, were associated with the…
In Mice, COVID-19 Leaves Nerve Cells Vulnerable to Further Injury
A prior COVID-19 infection in mice increased their susceptibility to nerve cell loss caused by MPTP, a neurotoxin known to…
Way of Producing Adult Nerve Cells Aids Memory, Eases Anxiety in Mice
A group of cells in the hypothalamus, a specific brain region, are responsible for stimulating the production of adult-born nerve…
FDA Seeks More Data Before OK’ing Extended Use Of Brain Electrodes
The U.S. Food and Drug Administration (FDA) has upheld its decision that the Evo stereoelectroencephalography (sEEG) electrode, designed to monitor…
DBS, but Not Medications, Seen to Ease Gait Changes Tied to Fall Risk
Gait variability, or changes in stride while walking that associate with a greater risk of falls in people with…
Phantom Smells More Common Than Once Thought, Study Suggests
Olfactory hallucinations (OH), or phantom smells, were present in over 18% of people with Parkinson’s disease and were associated…