Researchers have found a compound that can rescue dopaminergic neurons from cell death and improve locomotor activity in fly models of Parkinson’s disease. Their findings were published in a study, “Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models,” in the journal…
Gocovri (amantadine) extended release capsules work to help lessen dyskinesia, or involuntary muscle movement, and off episodes in Parkinson’s, but special care needs to be given elderly patients with poorer kidney function, according to data presented by Adamas Pharmaceuticals, the treatment’s developer, at a science conference. Renal…
People with Parkinson’s disease who have a specific mutation in the LRRK2 gene may be 10 times more likely to develop leukemia, and twice as likely to have colon cancer, researchers report. The researchers say this particular patient population should be closely monitored and screened for the early…
People taking Hytrin (terazosin) or similar medications to treat high blood pressure and benign prostatic hyperplasia may be less likely to develop Parkinson’s disease, an early study suggests. Parkinson’s patients who use these medications may also see their disease progress more slowly and with fewer complications, its researchers report.
Use of Inbrija (levodopa inhalation powder) helps to effectively manage off episodes in Parkinson’s disease without an increase in troublesome dyskinesia, or involuntary muscle movement, according to data being presented by Acorda Therapeutics at the International Congress of Parkinson’s Disease and Movement Disorders. Results from…
Dopaminergic therapy may ease difficulties with gesturing and using tools in people with Parkinson’s disease by improving brain connectivity between the cognitive and motor regions, a study has found. The study results, “Dopaminergic modulation of the praxis network in Parkinson’s disease,” were published in NeuroImage: Clinical.
Explosions that cause even mild traumatic brain injury can trigger molecular changes that, later in life, lead to neuroinflammation and degeneration, and a greater risk of Parkinson’s disease. But work by researchers at Purdue University also found that analyzing urine levels of a compound called acrolein may help within days of…
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has awarded AC Immune a new grant to further the development of tracer compounds for Parkinson’s disease (PD). Specifically, this award continues MJFF support for AC Immune’s alpha-synuclein positron-emission tomography (PET) tracer program, aiming for an accurate imaging agent…
Singing a rhythmic tune out loud or, even better, simply listening to it play in your head can help older adults — including those with Parkinson’s disease — to walk more naturally and at a steadier pace, a study reports. The study, “Mental Singing Reduces Gait Variability More Than…
Fatigue in Parkinson’s disease may be a clinical manifestation of low diastolic blood pressure — the second number presented in a BP measure, according to recent research. The study, “Fatigue in Parkinson’s Disease Associates with Lower Ambulatory Diastolic Blood Pressure,” was published in the Journal of…
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