Sunbird Bio’s blood test to indirectly detect toxic clumps of alpha-synuclein protein in the brain, a hallmark of Parkinson’s disease, may help yield an accurate Parkinson’s diagnosis, according to data from a clinical study. The company presented the results in a poster, “Using neural derived EV-bound biomarkers in…

Booster Therapeutics announced its launch and the start of work into therapeutics that improve the body’s ability to clear itself of the defective, disease-causing proteins that drive Parkinson’s disease and other neurodegenerative conditions. The company, which is based in Berlin and whose opening was supported by $15 million…

The Centre for Medicines Discovery at the University of Oxford and BPGbio, an artificial intelligence (AI)-focused biopharmaceutical company, established a five-year research collaboration that aims to advance new technologies for treatments for people with brain diseases like Parkinson’s who have limited options. Together the partners will validate and…

A National Institutes of Health (NIH) grant will fund the creation of a brain-on-a-chip technology, a microengineered device containing nerve cells and blood vessels to help scientists more fully understand how neurodegenerative diseases like Parkinson’s and Lewy body dementia affect their ability to function. Jungwook Paek, PhD,…

Having acute kidney injury increases the risk of developing dementia, including Parkinson’s disease with dementia, according to a study that suggests that people with kidney damage may benefit from close monitoring for early detection of cognitive decline. “Identifying acute kidney injury as a risk factor for dementia can lead…

The nonprofit SPARK NS has announced the five recipients of the 2024 SPARK NS Parkinson’s Disease Translational Research Program that’s designed to foster the clinical development of promising therapies for Parkinson’s disease. The two-year program provides each scientist with up to $2 million, depending on the achievement…

A buildup of fat-like lipid molecules may help to promote the inability of dopaminergic neurons, the nerve cells that are lost in people with Parkinson’s disease, to divide and grow as they should, researchers suggest. Further understanding of the role of lipids in neurodegeneration “has the potential to open…

A protein called STAT3 protected nerve cells from degeneration and improved behavioral and motor outcomes in a rat model of Parkinson’s disease, a study reveals. STAT3 potentially offers “a new avenue for treatment against Parkinson’s,” researchers wrote in the study “STAT3 protects dopaminergic neurons against…

Researchers have developed a new mouse model that affects nerve cells in the eye that could help in studying disease mechanisms and treatment approaches in Parkinson’s disease. The mice are lacking the protein VPS35 in specific cells of the eye and developed protein deposits that contain alpha-synuclein, neurodegeneration, and…

Nearly one-quarter of deceased athletes with chronic traumatic encephalopathy (CTE), a neurodegenerative disease associated with repetitive head impacts, experienced Parkinson’s disease-like symptoms during their lives, according to a study researchers said is the largest to date exploring the links among contact sports, CTE, and parkinsonism. The researchers found that…