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When most people think about Parkinson’s disease (PD), they focus on movement problems almost exclusively. But mild cognitive impairment is among other potential disease symptoms, although medical professionals and researchers currently disagree on the extent and exact nature of this problem in Parkinson’s patients. Progressive tremors and rigidity occur in PD largely due to the…

Lund University researchers have shown that cerebrospinal fluid (CSF) biomarkers of angiogenesis are raised in Parkinson’s disease (PD) patients and are related to walking and balance difficulties, blood-brain barrier (BBB) increased permeability, and white matter lesions (WMLs). The research study, entitled “Increased CSF biomarkers of angiogenesis in Parkinson Disease”…

Researchers from the University of Kentucky presented the results of their research on a potential novel therapy for the treatment of Parkinson’s disease. The poster presentation, entitled “Therapeutic Development of siRNA targeting Alpha-Synuclein,” was part of the Michael J. Fox Foundation (MJFF) Parkinson’s Disease Therapeutics Conference held in…

A new case control study evaluated the association between caffeine consumption and risk of developing Parkinson’s disease (PD) in patients with high and low genetic susceptibility. The paper, entitled “Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson’s Disease,” was published in Scientific Reports. Parkinson’s disease,…

A recent published paper in Alzheimer’s & Dementia: the journal of the Alzheimer’s Association entitled “Improving the Clinical Detection of Lewy Body Dementia with the Lewy Body Composite Risk Score,” reports a new quick test to determine signs and symptoms of Lewy Body dementia…

Findings from a recent study published in the American Journal of Preventive Medicine revealed an association between increasing hours of television viewing per day and risk of death from its major causes in the United States, including Parkinson’s disease. TV viewing is the most prevalent of leisure-time behaviors…

University of Dundeen scientists have uncovered the molecular mechanisms and targets under the effect of a specific gene mutation involved in Parkinson’s disease development and which could prove to be strong targets for new therapies and even early disease detection. The paper entitled “Phosphoproteomic screening identifies Rab GTPases as novel downstream targets…

Recent research identified a new technology that can successfully deliver drugs across the blood-brain barrier, conferring neuroprotection in a mouse model of Parkinson’s disease. The study entitled “Heterotopic Mucosal Grafting Enables the Delivery of Therapeutic Neuropeptides Across the Blood Brain Barrier” was published in Neurosurgery…

In a recent paper published in The Lancet Neurology, researchers evaluated the analgesic effect of prolonged-release oxycodone-naloxone (OXN PR) in patients with Parkinson’s disease (PD) suffering from severe and chronic pain in a pioneer Phase II clinical trial. Pain is a very common, non-motory symptom in PD patients (approximately 60% of patients)…

Parkinson’s UK, the largest charity funder of Parkinson’s research in the U.K., recently launched a new research project that explores the possibility of using an individual’s skin odor to diagnose Parkinson’s disease. Watch the video below to learn more about this new project from Parkinson’s UK’s director of research, Arthur Roach:…