Treatment with investigational antibody therapy prasinezumab tended to slow the progression of motor symptoms in people with early-stage Parkinson’s disease in a Phase 2b trial, with particularly pronounced benefits among those also receiving levodopa. However, the difference between prasinezumab and a placebo in the overall study population…
News
Tracking how the brain responds to different emotions may be an effective way to detect Parkinson’s disease, a new study posits. The study, “Exploring Electroencephalography-Based Affective Analysis and Detection of Parkinson’s Disease,” was published in Intelligent Computing. Along with its characteristic motor symptoms, Parkinson’s can…
Adaptive deep brain stimulation (aDBS) resulted in long-lasting relief from bradykinesia and walking difficulties in a 61-year-old Parkinson’s disease patient, whose quality of life also improved, researchers wrote in a case report about the man. Unlike conventional DBS (cDBS), where electric brain stimulation is constant or adjusted manually…
In people with Parkinson’s disease, shrinkage in tremor-related brain areas is associated with the progression of motor symptoms, according to a study. In the brain’s gray matter, which contains cell bodies of neurons, this shrinkage, or atrophy, of tremor-related regions and the whole brain over two years was associated…
A diet rich in antioxidants — such as vitamins A, C, E, and selenium and zinc — may help most older adults counter becoming frail, but its benefits are less certain for people with Parkinson’s disease, a study drawing on U.S. data suggests. Findings indicate that the disease’s complex…
A 45-year-old man initially deemed to have depression was later diagnosed with parkinsonian syndrome following a skin biopsy that detected alpha-synuclein, a protein that forms toxic clumps in the brains of people with Parkinson’s disease, according to a case study from researchers in Miami. After receiving a combination of carbidopa…
Having foot pain, particularly of mild intensity or occasional pain, is associated with a higher risk of falls among people with Parkinson’s disease, a study in Spain shows. The study assessed the factors that could contribute to a higher risk of falls with Parkinson’s and found that people with…
A consortium dubbed Center Without Walls is planning to begin human testing of specific positron emission tomography (PET) radiotracers, which its scientists identified, to detect toxic proteins like alpha-synuclein, helping diagnose and monitor Parkinson’s and similar diseases. Funded by a five-year, $30 million grant from the National Institutes of…
A syndication model being explored in a Parkinson’s disease study may help accelerate digital healthcare by speeding the development of digital tools to track disease activity, according to a published paper. “The syndication model combines the speed of single sponsor studies with the advantage of having multi-member expertise and…
The U.S. National Institutes of Health (NIH) launched a consortium to support clinical studies designed to better understand the link between the gut and brain in Parkinson’s disease. The Gut-Brain Communication in Parkinson’s Disease Consortium is motivated by the fact that there are compelling data indicating that the gastrointestinal…
Recent Posts
- Being mad at each other and mad at Parkinson’s disease, too
- Parkinson’s muscle firing patterns different for women than for men
- Breathing CO2 activates brain cleanup signals in new Parkinson’s study
- Guest Voice: DBS surgery transformed my life with early-onset Parkinson’s
- Smartphone app helps Parkinson’s patients map daily symptoms