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Parkinson’s Institute and Clinical Center, Retrotope Collaboration to Test RT001 in Progressive Supranuclear Palsy

Parkinson’s Institute and Clinical Center and Retrotope have paired up to explore the therapeutic potential of the investigational agent RT001 in patients with progressive supranuclear palsy (PSP), a type of treatment-resistant Parkinson’s disease. Under Retrotope’s expanded access program for RT001, the institute’s physicians started dosing two…

New Compound Can Prevent Formation of Toxic Alpha-Synuclein Aggregates, Animal Study Finds

A newly identified small molecule compound, called SynuClean-D, can prevent the formation of toxic alpha-synuclein aggregates, disrupt the propagation of amyloid fibrils, and rescue nerve cells from alpha-synuclein-induced death in an animal model of Parkinson’s disease, a study shows. Given this particular activity, SynuClean-D may be a promising candidate…