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Specific Dopamine-producing Neurons Crucial to Adaptive Movement, Early Study Finds

Dopaminergic neurons — nerve cells gradually lost to Parkinson’s progression — that contain an enzyme called aldehyde dehydrogenase 1A1 are essential for acquiring the motor skills needed for proper movement in given situations, a mouse study reports. The research, “Distinct connectivity and functionality of aldehyde dehydrogenase 1A1-positive nigrostriatal dopaminergic…

h-Patch Device for Slow Apomorphine Infusion May Ease Off Periods in Advanced Parkinson’s, Valeritas Says

Under-the-skin infusions of low-dose apomorphine using a wearable device called h-Patch may help in avoiding off periods and improving motor function in Parkinson’s patients, Valeritas, the technology’s developer, reports. A preclinical study found that apomorphine delivered using h-Patch could be detected in the blood within two hours, with a…

Parkinson’s Foundation Names Three New Centers of Excellence

The Parkinson’s Foundation has added three Centers of Excellence to its international network of expert care providers for Parkinson’s disease  patients. The new centers are the University of Colorado Movement Disorders Center, Jefferson Health’s Comprehensive Parkinson’s Disease & Movement Disorder Center, and Indiana University…