Researchers Work to Map LRRK2 Cell Interactions for Parkinson’s Clues, Study Says
Researchers characterized the structure and interactions of proteins connected to the leucine-rich repeat kinase 2 (LRRK2) gene, the most…
Articles by Margarida Azevedo, MSc
IGF-1 May Be Involved in Parkinson’s Development, Review Suggests
Increasing evidence links insulin-like growth factor 1 (IGF-1) deficiency to the development and progression of Parkinson’s disease, a…
Researchers Identify Promising Targets in Molecular Pathway Involved in Sporadic Parkinson’s Disease
Researchers at the Buck Institute for Research on Aging have learned that oxidative stress, a main driver in sporadic Parkinson’s Disease, affects…
Heart Drug Found to Slow Plaque Build-up in Blood Vessels in the Brains of Mice
Platelets contribute to amyloid-β deposits in blood vessels in the brain by promoting the formation of Aβ aggregates that are central…
Inhibition of 2 Enzymes Seen to Reverse Parkinson’s Movement Problems in a Fruit Fly Model
Two enzymes that play an important role in the pathogenesis of neurodegeneration, and whose inhibition was seen to improve disease symptoms…
Researchers Develop and Share 10 Stem Cell Lines with Common Parkinson’s Mutations
Scientists at the Buck Institute for Research on Aging have derived 10 induced pluripotent stem cells (iPSC) lines from Parkinson’s disease (PD) patients…
Parkinson’s Patient, After Nerve Cell Transplant, Showed ‘Major’ Benefits for Nearly 25 Years
Lund University researchers followed a Parkinson’s disease patient who had undergone neuronal transplantation, and reported the patient experienced long-term “major clinical benefits,” including…
Overactive Innate Immune System Seen as Underlying Cause of Neuronal Death in Parkinson’s
Chronic activation of the innate immune system, the body’s first line of defense, is the main cause of a range…
Neuronal Changes Seen in Parkinson’s Mouse Model Well Before Disease Symptoms
University of Texas Health Science Center researchers have identified physiologic changes in dopamine neurons in a key animal model of Parkinson’s known…
Coffee’s Health Benefits May Include Reduced Risk for Parkinson’s Disease, Scientists Report
Coffee is one of the most consumed drinks in the world, with U.S. consumers spending an average of $40 billion…