When combined with deep brain stimulation (DBS), a dynamic, cycling-based exercise program for people with Parkinson’s disease produces changes in brain activity indicative of potential neural rewiring, according to a study. The research was conducted at University Hospitals in Cleveland and the Veterans Affairs Northeast Ohio Healthcare System,…
Infection with a common and otherwise harmless virus called human pegivirus (HPgV) might play a hidden role in Parkinson’s disease, particularly for those with specific genetic risks, according to a new study. “For a virus that was thought to be harmless, these findings suggest it may have important effects,…
Neu Health is launching its smartphone-based system to measure tremors in people with Parkinson’s disease in the U.S. The Food and Drug Administration (FDA) has cleared the company’s digital tool to track Parkinson’s symptoms remotely, which uses only a smartphone to measure tremor severity, reducing reliance on wearables…
Neuraxpharm is partnering with Dizlin Pharmaceuticals on Dizlin’s Infudopa SubC drug-device combination therapy, which allows for continuous levodopa-carbidopa delivery in people with advanced Parkinson’s disease. Infudopa SubC is a wearable device being developed for patients who experience fluctuations in their Parkinson’s motor symptoms despite treatment. “Our…
An experimental theater program improved the emotional well-being of people with Parkinson’s disease, and eased their anxiety and depression, a study reports. “Arts-based interventions could offer a novel, efficient, and inexpensive tool to complement pharmacological therapy,” the study’s researchers wrote. The program outperformed an at-home memory and attention program at…
Ambroxol, a common cough medicine, may help stabilize neuropsychiatric symptoms in Parkinson’s disease dementia (PDD) and shows cognitive promise for patients with mutations in the GBA1 gene, according to results from a Phase 2 clinical trial. While ambroxol is widely used in Europe to treat respiratory conditions, it’s not approved…
Genetic analysis of saliva may offer a noninvasive way to assess the risk of developing Parkinson’s disease, according to a saliva-based DNA study led by researchers at the University of the Basque Country (EHU) in Spain. The scientists found that molecular markers in saliva can reflect whole-body disease processes,…
Pharmather is advancing its ketamine-based treatment for Parkinson’s disease as the approval decision date of Aug. 9, 2025, set by the U.S. Food and Drug Administration (FDA) draws closer. If approved, the company plans to market the product under the brand name Ketarx and expand its use in neurological conditions,…
BioVie’s ongoing SUNRISE-PD clinical trial of bezisterim in early Parkinson’s disease uses a hybrid, decentralized approach to center patient experience and promote accessibility, according to the company. Parkinson’s disease patients often face barriers to accessing specialized care and participating in clinical trials due to delayed diagnosis, limited mobility, and…
Neuron23 has dosed the first participant in its Phase 2 clinical trial of NEU-411, an investigational treatment for early Parkinson’s disease that targets overactivity in the LRRK2 enzyme. The therapy may benefit individuals with genetic mutations or variations in the LRRK2 gene, which is a key contributor and…
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