Under-the-skin infusions of low-dose apomorphine using a wearable device called h-Patch may help in avoiding off periods and improving motor function in Parkinson’s patients, Valeritas, the technology’s developer, reports. A preclinical study found that apomorphine delivered using h-Patch could be detected in the blood within two hours, with a…
A virtual reality game being created by engineering students, called “Overcome,” aims to offer Parkinson’s patients safe and fun ways of taking part in rehabilitation sessions that might preserve walking and mobility skills. Though players of all ages may find the game entertaining, “Overcome” is intended for adults…
A highly sensitive “sniff-cam” is able to detect tiny levels of ethanol in the breath even without alcohol consumption, according to new research. The findings suggest potential applications in studies of Parkinson’s, diabetes, and cancer. The study, “Ultrasensitive Sniff-Cam for Biofluorometric-Imaging of Breath Ethanol Caused by…
Research conducted aboard the International Space Station will look at how nerve cells interact with key immune cells of the brain in low-gravity conditions. The goal is to better understand nervous system damage in Parkinson’s disease and multiple sclerosis (MS) — and help improve their treatments. “This…
The coupling of electrical signals in the brain — as it responds to levodopa and is associated with motor improvements — may provide ways to better assess the clinical state of people with Parkinson’s disease, and improve the efficacy of deep brain stimulation (DBS), according to new…
Inflammatory molecules called cytokines may be a peripheral biomarker of Parkinson’s progression, especially of its characteristic changes in motor abilities, according to new research using machine learning. The study, “Parkinson’s progression prediction using machine learning and serum cytokines,” appeared in the journal npj Parkinson’s Disease.
Treatment with Accordion Pill-Carbidopa/Levodopa (AP-CD/LD) did not provide greater reduction in daily off periods in adults with advanced Parkinson’s disease compared with Sinemet, according to top-line results of a pivotal Phase 3 trial. However, an ongoing analysis shows meaningful decreases in specific subgroups of patients, the team…
Treatment with the naturally occurring antioxidant N-acetylcysteine (NAC) along with standard Parkinson’s therapies improved patients’ motor and mental abilities, possibly by restoring the function of dopamine-producing nerve cells, according to new research. The study, “N-Acetyl Cysteine Is Associated With Dopaminergic Improvement in Parkinson’s Disease,” appeared in…
An oral combination that includes Aricept (donepezil) — an Alzheimer’s therapy — and Ginkgo biloba improved cognitive abilities and quality of life in people with Parkinson’s disease dementia (PDD) treated for six months, a study from China reports. The study, “The efficacy of a ‘cocktail therapy’ on…
Twice daily treatment with ThermoNeuroModulation (TNM), a non-invasive device for at-home use, provided sustained motor and non-motor benefits and was associated with high satisfaction in a small group of Parkinson’s patients on standard medications, a clinical trial reports. The study based on its findings,“Caloric vestibular stimulation for the…
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