Inês Martins, PhD,  managing science editor—

Problems with vision are more common in older people with Parkinson’s disease than in others of a similar age, and are linked with poorer health outcomes, a study based on U.S. Medicare records found. Fewer than 60% of the more than 285,000 Parkinson’s patients whose data were analyzed, however, had…

People with Parkinson’s have postural adjustments even at early stages of the disease when clinical symptoms of postural instability are not evident and despite the use of antiparkinsonian medications, a recent study shows. Researchers believe these findings suggest that postural behavior may be used as an early indicator to…

Nuplazid (pimavanserin), an approved therapy for treating hallucinations associated with Parkinson’s disease psychosis, is generally safe and well-tolerated in the long run, and may be associated with reduced mortality in this particular patient population, findings from a long-term extension study suggest. The results were presented at the…

Deep brain stimulation with Boston Scientific’s Vercise system led to sustained “on” periods without troublesome dyskinesia and improvements in both motor and non-motor symptoms of Parkinson’s disease for at least one year, updated findings from the INTREPID trial show. Use of the Vercise Deep Brain Stimulation system in…

Chemicals in diesel exhaust can trigger the formation of toxic protein clumps and the death of nerve cells — hallmarks of Parkinson’s disease — by preventing the cell’s natural disposal mechanisms from working properly, a study in fish and human cells shows. The findings also demonstrated that boosting these cellular…

Infections with the new coronavirus may manifest in people with Parkinson’s as a rapid worsening of disease symptoms, hindering early and accurate diagnosis of infections in this population, according to a case report on two patients. It also points to a possibility of more severe infections in these patients, but…

The U.S. Food and Drug Administration has approved Sunovion’s Kynmobi (apomorphine hydrochloride) as an on-demand sublingual treatment for off episodes, or times when medication wears off, in people with Parkinson’s disease. The medication, formerly known as APL-130277, is an apomorphine film that is placed under-the-tongue (sublingual administration) when…

Intec Pharma and its manufacturing partner, Lohman Therapie-Systeme (LTS) have shown an ability to manufacture the Accordion Pill Carbidopa/Levodopa (AP-CD/LD), an investigational Parkinson’s therapy, at a commercial scale, and are advancing with the production of stability lots expected to bring it into a new Phase 3 trial. Meanwhile, Intec is…

People with early-stage Parkinson’s disease and non-motor symptoms such as depression, anxiety, urinary tract issues, and hallucinations or delusions are more likely to experience sleep disorders, a recent study has found. Better cognitive function appears to predict better sleep quality in these patients, according to the…

People who drink more caffeinated beverages and have high blood levels of urate appear to have a significantly lower chance of developing Parkinson’s disease, a study has found. While the research provides further support that caffeine and urate are protective factors against Parkinson’s, scientists caution that the therapeutic potential…