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Entacapone
Does anyone have any experience with entacapone? My MDS just prescribed it to extend my on times.
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8 Replies
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From a PD point of view this was probably the best medication I have tried, unfortunately it was accompanied by an unacceptable level of diarrhoea.
Brian Bickers -
My wife has been taking entacapone for a year, starting with half a pill to one whole one. She has many symptoms that are hard to ascribe to a single factor, as happens with most PD patients, but none of the symptoms have persisted even as she continues to take entacapone.
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It seemed to improve my on time but unfortunately I had some acute anxiety attacks that I felt were tied to entacapone, and I didn’t have more of them since I stopped the med. As I recall, it also messed with my sleep cycle.
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Yes, I take entacapone for about 8 months now and it seems to prolong my on times by about an hour.
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Dyskinesia is my most annoying off time. Entacapone made it worse. The thing that helps the most for me is SAM-e and DHEA first thing in the AM. SAM-e is best taken on an empty stomach at different times from other meds which can make timing tricky, but it eliminates dyskinesia and improves my mood.
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I developed what I call “screaming diarrhea”. I stopped the entacapone and then started it again and the diarrhea came back. This happened three times. Needless to say I do not take any more. I wish you luck.
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I started with Entacapone but within a few weeks I too had diarrhea which is unusual for me because I’m usually constipated. So I switched to the brand name of COMTAN and have had no diarrhea since. I think it may have had something to do with the inactive ingredients, but not sure.
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Tried it with no noticeable benefit.
I have more off days than off periods in a day.
My main side effects of my is blood pressure variations.
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