fakhiuddin ahmed

It will be my wife’s decision, but I will take the boosters and vaccines and she has followed my example this year. In the past she did not take the flu vaccine but since COVID’s appearance, she has been taking the flu vaccines as well–likely because these vaccines are brought to our door in our senior living place. Neither of us had flu or covid.

Speech problems seem to disappear when my wife is in the “on” period and sometimes, speech symptoms are the most apparent symptom of the “off” period.

I have also noticed that depression and other cognitive problems occur independently in the off periods. With my neurologist’s acquiescence, I will try, levodopa/carbidopa ODT and see if it helps.

My wife, with PD, and I live in a senior care facility that provides meals as well living accommodations. Her major symptoms are fatigue, slurred speech, periodic cognitive problems. We have help coming 3 times a week for 4 hours to help her bathing, getting dressed and taking her to her classes. So far this has worked to some degree. I had…[Read more]

My wife was diagnosed 25 yrs ago, when she was 55yrs old, but became symptomatic about 5 yrs ago. DBS took care of tremors and dyskinesia, but her symptoms, of sleepiness, cognition changes, slurred speech, fatigue, depression, kyphosis, remain problematic. Like so many, I have to consider that these are due to disease progression and or drugs…[Read more]

Has he had a CT with contrast or MRI of head done recently? My wife feels very hot, actually sweating when the ambient temps are comfortable for the rest of us. this was ascribed to dialatation of skin vessels under control of sympathetic/para sympathetic nervous system which goes awry in P.D.Could this be happening to the intracranial vessels?…[Read more]

My wife’s speech is often difficult and sometimes, impossible for me to understand,, despite speech therapy. This may be due to my hearing aid which improves some sounds and not others.

My wife does not drink enough liquids despite my pleas(her urine is dark) and she is often confused. I wonder if there is evidence that dehydration is the cause…[Read more]

While I do not have any experience with this device, I cannot see the rationale for it. However, I just read that B12 injections help. I wonder if B12 levels were low in patients who were helped and many other questions.

So many people have had successes with so many types of treatments that it is tempting to deny any cause and effect. My wife has had leg cramps at various times of the day,but mostly at night for the last thirty years. She lost her sense of smell decades ago, was diagnosed with PD25 yrs ago, but became disabled 8 yrs ago. She has tried many…[Read more]

My wife does. She is sweating when the room temp is 65 degrees. Her docs do not think she is crazy since it is well known that the sympathetic nervous system that governs relaxation or constriction of small blood vessels in response to ambient temperatures are also affected by PD. We just adjust our clothing.

Is there a description of advanced PD? Do they become immobile, incontinent, unable to feed themselves or by meds and other treatments, few if any patients ever reach such a state? Does cocaine or cannabis help?

My wife used to like singing and hear her own singing recorded on CDs, but now, rarely does she sing or put the CD s on. Often, she just sits not wanting to read or watch TV. She seems to require me to interact with her and not do my work.

My wife with PD suffers from depression, at times severe. The covid has separated her from friends. She feels weak and spends greater time in bed and it is difficult to determine if her fatigue is from depression or PD or likely both. Her exertion tolerance has progressively decreased, which makes me want to know how close to the end she is. I…[Read more]

My wife has been taking entacapone for a year, starting with half a pill to one whole one. She has many symptoms that are hard to ascribe to a single factor, as happens with most PD patients, but none of the symptoms have persisted even as she continues to take entacapone.

not knowing(will look up literature) I cancel whatever activity we were planning and let her rest.don’t know the experience of marijuana use but doubt if she will try that. If my energy is spent, I improvise.

I would not advise snow clearing for elderly folks. One fall resulting in a hip fracture may be extremely dangerous depending upon your age and general fitness. Many places have free services for elderly or disabled people in N.Y. maybe yours does too. sorry for this pessimistic opinion.

Please encourage folks to send follow up research projects they have come across. Curing PD in mouse models is exciting but any follow up data on how long did the response lasted, did any morph into neoplastic lesions?

I want to have access to the studies underway, including stem cell transplantation, inducement of patients own stem cells to grow faster, invivo or exvivo, exchange of csf etc.

Thanks

f.ahmed md

My wife.