Dyskinesia is defined as abnormal, uncontrollable, involuntary movements.
Continued use of high levels of levodopa, which are needed to manage movement symptoms as PD progresses, can cause chemical imbalances of their own or lead to large fluctuations in the amount of dopamine being released. This leads to dyskinesia.
In the the UK, there are trials being conducted that allow people in the more advanced stages of the condition to better manage their symptoms with fewer side effects:
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