Serotonin, norepinephrine, and dopamine are all chemicals involved in regulating mood, energy, motivation, appetite, and sleep. Also, the brain’s frontal lobe, which is important in controlling mood, is known to be underactive in people with Parkinson’s disease. It’s no wonder that people with Parkinson’s may look sad, but as Sherri Woodland writes, looking sad and feeling sad are two different things.
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