• Robert Li

    Member
    January 24, 2022 at 7:16 am

    Impulse control disorders or behavioral addiction reported in Parkinson’s disease include pathological gambling, hypersexuality, compulsive buying and binge eating.

    https://pubmed.ncbi.nlm.nih.gov/22921247/

    Hello Krit Singh Chand, I wanted to share this, which may help you reframe your conclusions and perhaps feel a little more positive, looking forward.

    There are genetic dopamine processing differences (primarily the COMT and DAT genes) that can predispose some of us to addiction, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, unusual sleep patterns, and even atypical response to caffeine.  These dopamine processing differences are not genetic defects, because they can have benefits, such as giving some of us excellent memories, unusual cognitive skills, or decreased need for sleep.

    There is a risk if we have naturally high levels of dopamine.  When dopamine is released, it is more vulnerable to oxidation reactions.  Oxidized dopamine can cause dystonia / pain, and in the long run can damage dopamine producing neurons.

    However, high levels of dopamine itself is not a risk.  The presence of toxins in the basal ganglia combined with dopamine increases the risk.   The most common source of toxins in the basal ganglia may be metal deposits due to exposure to long term industrial / metalworking / train track air pollution.  For more info, please see: https://www.hsph.harvard.edu/news/press-releases/significant-link-found-between-air-pollution-and-neurological-disorders/

    To reduce my air pollution exposure, I have a “True HEPA” filter in every room of my house.   I also have a small air quality monitor (<$100).   Finally, I don’t go out for more than a few minutes without an N95 mask, when http://purpleair.com in my area reads yellow or worse air pollution.  Call me paranoid but at least I can move again!