New PD Forum Moderator

Never tried Butyrate. have been on Niacin for 25 years for high cholesterol, diagnosed with Parkinson’s just a few years ago.

I don’t think the placebo effect works if you know it is a placebo.  The point of the placebo effect is that it occurs only when the patient believes they are taking something that works, as in a double blind study (or for example if you read about something in a nutrition mag and believe it, even if there is no scientific validity.) I believe…[Read more]

Ran behind the DDT truck as young child laughing in the fog many summer nights. Used to call it the “fogging man”. Big treat then. NOT NOW 🙁

The day  I got my diagnosis I presented with foot tremors. The neuro told me they could only be relieved with brain surgery.  However getting treated with carbidopa / levodopa and selegiline, they went away (for the most part).

OK will chime in…Bike 20 miles 3x per week on lifecycle. Takes me about 75 minutes and I do cognitive exercises at same time (when indoors obviously) utilizing ALZ life program on I pad (my own clinical trial, so to speak). Have gotten really good at Sudoku , haha.  Take the cycling outdoors with the sunrise on the weekends (afraid of COVID and…[Read more]

I have also been told that to get a similar effect with CBD one would have to take up to 50x or more CBD than is normally “prescribed” and this is associated with liver toxicity. Stated differently , to get the same beneficial effects using CBD versus micro dosed THC, one would have to take a toxic dose.

Mary- Here is the deal as I see it today (am always learning) after much consultation with respected physicians in the field…THC is not a placebo unlike CBD. Taken in relative “microdoses” (the only way to do this scientifically is with capsules, otherwise the actual ingested dose is guesswork, particularly if smoked), it does decrease anxiety,…[Read more]

I believe CBD is a placebo unless taken at extremely high and potentially toxic doses. It doesn’t bind to the receptors of the endocannabinoid system. It has been speculated that it may boost your body’s endocannabinoid production, but I don’t buy it. Any non-placebo effects of CBD are mainly from the THC in the oil.

Was also very excited by the study, but “years” is a bit depressing. I guess there are different stages of clinical trials, and it has to go through at least 4 before being approved.Maybe they can fast track it….

Hi all: Will stick my two cents in …

I totally understand the strong desire to avoid pharmaceutical dopamine replacement for PD  (I think this is part of the “denial” stage we all go through), but the medical studies do not support this as an effective form of treatment. It has been said you won’t die from Parkinson’s but with it. Dopamine…[Read more]

Thanks for sharing that Bob! Plan to  get another scientific opinion on this…

Meant to say latter two, not to. Now off to virtual boxing class, haha.

Meant to say latter two, not to. Now off to virtual boxing class, haha

For the record, I have been on Lion’s Mane, Magnesium, probiotics and many other supplements I researched and am on a strict diet since diagnosed a few years ago. I exercise like a maniac (for me), and am on an uber healthy diet. As a result,  I am actually in the best overall physical shape of my adult life, and my labs have never looked better…[Read more]

Dopamine boost directly into brain via inactivated virus. Immune modulated response attacking harmful brain protein accumulation. Effects of light and sound therapy on brain. Not exactly excited (more interested) but trying to stay positive.

I tried. Didn’t work. All of those things help and are worthwhile and even necessary adjuncts For a lot of reasons. but in the end it depends how much dopamine ur brain is producing. Over time the brain produces less not more so when the critical mass is reached  then we need some form of dopamine to replace what is lost. there really is no way ar…[Read more]

Alan: Glad this has helped you. I have also used 10 mg in the day, but do better with 20mg as an anxietolytic dosage, mainly at night. ( I get trying to keep your dose a low as possible, but unaware of any side effects at higher dosage.) I used to think that any THC was a bad thing, because the last thing I wanted was the jittery and paranoid…[Read more]

The short answer is yes. The benzos hang out in ur body and are cumulative. The half life of clonazepam, which seems to be the drug the neuro guys like for PD, is something like 40 hours, which means every time you take it half is still in your body up to 2 days later! (note: others are shorter but are still quite long.) The THC I am ingesting…[Read more]

Just thought I would add that I am not a fan of the benzodiazepines because of tolerance (need more and more for same effect over time), plus addiction potential (probably the least of our worries with PD but nonetheless a problem.) Plus I don’t like them in my body during the day (most have very long half lives) as I think exercise is a critical…[Read more]