“Traffic jams” that occur along nerve cells in the brain and disrupt the transport of mitochondria were found to be a significant cause of Parkinson’s disease, a study reports.
In particular, researchers found that alpha-synuclein protein aggregates, the hallmark of Parkinson’s, impair the movement of mitochondria, which provide energy to cells. This shortage in the energy supply leads to the loss of synapses, which are the junction between two nerve cells that allows them to communicate, and ultimately causes the death of these nerve cells.
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