Parkinson’s News Forums Forums Parkinson’s Treatment Therapies and Medications Is anyone taking Aricept (donepezil) for PD related dementia?

  • Is anyone taking Aricept (donepezil) for PD related dementia?

    Posted by Sherman Paskett on January 24, 2025 at 11:04 pm

    My neuro put me on donepezil to treat short term memory issues. In addition I take carbidopa/levodopa, rasagiline, and amantadine for PD symptoms. The donepezil seemed okay for a few days, then I started feeling extended off times, until after eight days of taking the stuff it felt like my PD meds weren’t working at all. Tremor and bradykinesia were well controlled until I started donepezil. Now I experience bradykinesia most of the waking hours (and more intensely than before), tremor several times a day and have only slept about two hours a night the past three nights. In addition I have added new symptoms: constant muscle pain and stiffness, vomiting, and diarrhea.

    Has anyone had a similar experience? If so, did you just go off the stuff, adjust your PD meds, or find an alternative?

    Sherman Paskett replied 2 weeks ago 1 Member · 0 Replies
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