Tagged: sinemet generic prolopa
- This topic has 8 replies, 5 voices, and was last updated 1 month, 1 week ago by
Jean Mellano.
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September 13, 2019 at 5:08 pm #15497
Jean Mellano
KeymasterSince Merck pulled Sinemet, I have had to go on generic carbidopa/levodopa. I feel much worse, even though I have tried 3 generic brands. I now experience mild dyskinesia which I did not have on Sinemet. Have you had bad experiences using generic? If so, how did you address the issue? Which generic?
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October 23, 2019 at 9:27 am #15924
Philippe Joly
ParticipantI have occasionally been given generic Sinemet and I found it to be 25 to 30% less effective (based on an overall guess, not a scientific assessment). Since then, I have always insisted on being given the brand product. And this was before the new Sinemet.
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October 23, 2019 at 4:04 pm #15932
Jean Mellano
Keymastermy experience with generic as well. you can still get the 25×100 brand sinemet where you live?
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October 25, 2019 at 2:31 am #15965
Gail Dons
ParticipantMy problem with the brand Sinemet was that it got crumbly in heat, and since I spend several months a year in very hot, un-air conditioned climates, it was especially difficult when I had to cut a tablet in half. The generic actually worked better for me there!
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October 25, 2019 at 6:00 pm #15977
Jean Mellano
KeymasterI did notice the crumbliness of sinemet when I cut the tabs in half so I got a more expensive cutter with a sharper blade lol.
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October 29, 2019 at 10:04 am #16035
Michael R. Scott
ParticipantWhen and why did Sinemet 25/100 get pulled of the market? I ordered a replacement of my 25/100 about 45 days ago and with the first pill, I noticed that the pill’s effectiveness fell from roughly 6 hours to 3 hours!….. And despite that, the price was the same!… 🙁
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October 29, 2019 at 2:43 pm #16042
Jean Mellano
Keymasterhh michaael, in NY, I found out in May this year brand Sinemet was no longer orderable. As to why, we will never know..I suspect it is no longer profitable for Merck since there are so many generics. The generics do not work well for me either. We are at the mercy of big Pharma 🙁 You might find this article interesting: https://slippedawayblog.wordpress.com/2019/06/16/sinemet-shortage-the-silence-is-deafening/
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October 31, 2019 at 9:13 am #16062
Jim Shotton
ParticipantMy Neurologist switched me to Prolopa and it appears to work well, without the on/off issues that I had. Propola is a Levodopa/Benserazide combo, more popular in Europe.
Gie it a try
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October 31, 2019 at 1:32 pm #16070
Jean Mellano
Keymasterjim, thanks for sharing that. it is not available in the USA, but I plan to ask my neuro about it. The generic C/L dont seem to work for me.
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This reply was modified 1 month, 1 week ago by
Jean Mellano.
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This reply was modified 1 month, 1 week ago by
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