Reply To: Fecal microbiota transplantation therapy for Parkinson’s disease

[Bolt Upright]

Thank you for asking Todd!  I should preface that I did not go to college but I am a very motivated learner.

My diet is a combination of the Wahls Paleo Plus Protocol and the Specific Carbohydrate Diet. I avoid all foods that are prohibited on either list.  And I avoid dairy even if it is approved. Here is a great resource for SCD: http://www.breakingtheviciouscycle.info/

There are 2 reasons SCD appeals to me:

1. There is some thought that bad bacteria is sitting in our gut getting fed by hard to digest food just sitting around.  SCD is based on only eating food where the molecules are easily digested, so food does not just sit around and ferment.
2. It seems the goal of FMT for PK would be to normalize the gut flora.  I found a study that showed the SCD could normalize gut flora on its own, as long as you still had some of the needed flora: https://pubmed.ncbi.nlm.nih.gov/33291229/

I think I am also usually in ketosis.  I only eat between the hours of 2 PM and 10 PM.

Supplements (everybody please remember I am diagnosed with REMSBD not PD):

I just today cut out a bunch of supplements.  These are what I removed (I may add things back. I was taking too many):

1. Idebenone (is being trialed to slow progression of REMSBD to PD/LBD).
2. Lion’s Mane.
3. NAC.
4. Glycen.
5. Magnesium L-Threonate.
6. Amazon brand Solimo probiotics.

Here is what I kept:

1. B1 500 mg in the morning.
2. Jigsaw Health Butyrex from T.E. Neesby 6 per day (2 with my B1, 2 at 2 PM with food, and 2 at 9 PM with food.
3. Curcumin with both meals. Make sure it is 95% curcuminoids.
4. 100 mg of selenium with 750 mg of Inositol because I have Hashimotos and I read a study where they converted a bunch of people with sub-clinical HT to euro-thyroid using about this protocol. I am not sub-clinical but it still seemed worth a shot to lower inflammation. There is a lot of thought people with HT should not take selenium and neither should men over 50.
5. Niacin 250 mg Time Released at night. There is a study of 47 PD patients on this dosage for a year and all of them had some improvement or no worsening of UPDRS scores. Small study and no control group but I take what I can find. Niacin works as an anti-inflammatory in both the brain and the gut. Niacin binds with the GPR109A receptor, which is anti-inflammatory. Butyrate binds with it too, just not as strongly, so I time my butyrate to be used when the niacin is out of my body.
6. And Melatonin 10 mg. It seems to make me sleep like a baby and there is evidence it is neuroprotective.

And tomorrow I add Zeolite Clinoptilolite powder. Supposedly it detoxes you whole body. And it fixes the leaky gut.  And is an antioxidant and anti-inflammatory. And calming. This is not from the moneymaking pages, this is from the NIH: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515299/

I’m kind of an outlier on the SCD and the Zeolite.  I look at everything and if it makes sense to my high school educated brain I might just give it a whirl.

I also have my Ambroxol but I am still on the fence. And I have a red light that I need to start pointing at my head.  Tomorrow!

Thanks, Bolt.