Barry Block

I recommend that if the current medicine is working, don’t mess with it. I tried changing my Sinemet CR to Stalevo and wound up with diarrhea. It’s often better to increase dosage rather than to change. Also note that medicines such has Sinemet cannot be taken with meals, particularly with protein-based foods as they interfere with brain-barrier…[Read more]

Thanks for the info. Please explain what 1/2 means as I am not familiar with that terminology. Does it mean one half dose or one of two daily doses?

I too have the LRRK2 G2019S variant. What brand and dose of dibenconzide do you take. Is it chewable or sublingual?

I’ll have my doctor give me a b12 injection. If it works, I can buy injectable B12 online. Ironically, it’s sold to pet owners, but cyanocobalamin is the same stuff. I’m a retired Dr., so I can self-inject it as necessary.

What dose of B11 is recommended. Where can it be purchased?

What dose of B11 is recommended to be taken with the B12?

I have been taking sublingual B12 5,000 mcg for two weeks. So far there is little or no change in my tremors. Someone o this site said that sublingual was as effective as IM injections. What have others found?

I too rely on Alexa, however what I’ve learned is that it’s more important to time my Sinemet so as not to interfere with my meals, particular ones with high protein. Taking my meds an hour prior to meals or two hours after has eliminated the off periods I once experienced. This is because the carbidopa does not have to compete with protein in…[Read more]

I take Sinemet at 7AM and Fage Greek yogurt with peanut butter at 9 AM to avoid or minimize any protein conflict.

I use Mucina Pruriens (Nutracost) 800 Mg as a supplement to Sinemet CR. I also eat Fava beans as snack. These supplements are helpful without side-effects.

I work out virtually 5 times a week. It is the most important and effective treatment for PD. I combine aerobics (Zumba), weight training (5 lbs), and yoga/stretching and include balance exercises. I also try to take a mile walk when the weather permits.  I am 73 and my PD has only progressed slightly in 3 years.

I stopped driving about 3 years ago. I could probably still drive if I had to, but why take the risk? Besides using Lyft and Uber save me money. No more high insurance bills, gas, tolls, parking, depreciation, registration and inspection fees, and maintenance.

I will have no hesitation, The odds of a PD patient being hospitalized or dying are at least four times greater that of a non-PD patient! Res Ipsa Loquitur!

The bottle I have says three capsules per day. I like to follow directions.

After 1 week no noticeable change.

I just started it a few days ago. I bought capsules from Amazon (Nature’s Nutrition 1950 mg TID. I tried writing to the study’s authors to find a source, product and dosage, but got no reply. I not sure that Turmeric curcumin is equal to turmeric essential oils, but at about 10 cents a capsule it’s a low cost low risk. The indications are joint,…[Read more]

Please keep us posted.

I have to agree with Denise. Exercise is the very best thing that helps the symptoms of PD. I exercise 5 days a week with virtual classes (both aerobically and with 5 lb. weights). I have not increased my sinemet CR in 2 years and have no dyskensias or freezing. My balance is better than most 72 year olds and my cognitive abilities are only…[Read more]

I tried mannitol and all it gave me was loose stools. I have the LRRK variant of PD, so perhaps it works on other types of PD. I did have good results eating Fava beans, which are a natural source of L-dopa. These days, I add a daily Macuna capsule to my sinemet CR.

I am currently taking Lactobacillus plantarum but have yet to see a change. I tried mannitol, but it gave me diarrhea.

If you have a great PD doctor and a little luck, you will start on the right dose. I started on Sinemet 3 x a day. Later, when I reported sleeping problems, he added a 4th dose at night. I also find that a bag of fava beans or taking a macuna capsule helps when I need a boost.