[John]

Hello

1mg of Clonazepam each night is what works for me. Originally started on 0.5mg.

Good luck!

John

[John]

Try magnesium cream massaged into the affected area – a good one is EpZen Sleep Magnesium Body Lotion.

[John]

Thanks for the replies thus far. There was an article written about Symprove recently in these daily updates that first introduced me to the product:
https://parkinsonsnewstoday.com/2021/07/12/probiotics-alter-gut-microbes-reduce-some-signs-gut-inflammation-parkinsons/

So was just interested if any happened to be taking it already.

 

[John]

Hi All,

Thanks again for all the great suggestions.

After some further investigation and trials by myself I found that it was the Entacapone in the Stalevo I was taking that was causing the cramps at night.  Moving over to Sinemet CR helped resolve the problem.

[John]

Thanks everyone for your suggestions and advice – much appreciated!  I have tried magnesium as well but it didn’t help me unfortunately – I think it’s for normal leg cramps rather that than the wearing off effect of levadopa overnight.  I looked up oprymea and seems to be the European name for pramipexiole – the Dopamine Agonist. Yes that would definitely help but unfortunately I can’t take those types of Parkinson’s drugs due to other unwanted side effects. I am just on Stalevo 4 times a day and a slow release Sinemet before bed.  I have also tried taking quick release madopar at night when the cramps occur – but that didn’t help as well unfortunately.

[John]

<p style=”text-align: center;”>Hi All,</p>
I have had Parkinson’s for about 6 years – tried taking a locally sourced (Australia) Mannitol about a year ago for a few months – unfortunately for me no impact or improvement whatsoever.

Oh well – at least worth a try based on some people’s experience – but obviously doesn’t work for everyone.

Cheers

John