News

Plant of Indian Medicine Seen to Ease Insomnia, Restless Leg Syndrome

Adding a plant-derived agent called Withania somnifera, used in traditional Ayurvedic medicine and thought to help with disturbed sleep, to the insomnia medicines given a woman with Parkinson’s disease appears to have eased her insomnia and completely alleviated her restless leg syndrome, researchers in India report. The case report, “…

MJFF Grant Supports Work Into Potential of Sigma-2 Receptors

Cognition Therapeutics has received a grant from the Michael J. Fox Foundation (MJFF) for Parkinson’s Research to support preclinical work into two potential sigma-2 receptor modulators for Parkinson’s disease. The Therapeutic Pipeline Program Grant award, whose amount and duration were not specified, will help to fund studies of these…

MJFF Awards Grant to Cantabio to Develop Tau-focused Therapy

Cantabio Pharmaceuticals has been awarded a grant from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to develop a small molecule that can reduce the aggregation of a protein called tau. The research may have applications in treating Parkinson’s and other brain diseases. “We are proud…

Patients in Need of Levodopa Add-on Rate 3 Treatment Classes in Trial

In treating Parkinson’s symptoms that aren’t being adequately controlled by levodopa, monoamine oxidase type B (MAO-B) inhibitors are better than catechol-O-methyltransferase (COMT) inhibitors, according to patient-reported assessments in a clinical trial. The real-world study found no difference in effectiveness between MAO-B — like COMT, a dopamine reuptake inhibitor —…

Aerobic Exercise Stabilizes Motor Progression, Helps Cognition

Aerobic exercise stabilizes progression of motor symptoms and improves cognitive function in people with Parkinson’s disease, according to additional data from the Park-in-Shape clinical trial. Notably, these benefits were found to be associated with increased neuronal connectivity in brain areas controlling such functions and with reduced brain atrophy (shrinkage). These…

Early Use of Gocovri Could Delay Levodopa-induced Dyskinesia: Study

Early treatment with Gocovri (amantadine) may delay the onset of dyskinesia, the uncontrolled movements that are a common side effect of levodopa use, according to a new study. The study, “Amantadine Treatment and Delayed Onset of Levodopa-Induced Dyskinesia in Patients with Early Parkinson’s Disease” was published…

Top 10 Parkinson’s Disease Stories of 2021

All through 2021, Parkinson’s News Today brought you coverage of cutting-edge science and developments in treatment related to Parkinson’s disease. Here are the top 10 most-read Parkinson’s news stories of the year. We look forward to continuing to cover news for the Parkinson’s community in 2022. No. 10 – “…

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