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January 15, 2019January 21, 2019

New DBS Method Eases Both Cognitive and Motor Symptoms in Parkinson’s Patient, Study Shows

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A new approach to deep brain stimulation (DBS) was able to reduce both motor and cognitive impairments in a patient with Parkinson’s disease, a case study reports. Described by the ... Read more

January 14, 2019January 14, 2019

Sirion and Denali Collaborating to Develop Gene Therapies for Neurodegenerative Diseases

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Sirion Biotech and Denali Therapeutics have agreed to partner on the development of gene therapies for Parkinson’s disease and other neurodegenerative disorders. According to the license and collaboration agreement, the two ... Read more

January 14, 2019January 17, 2019

Nuedexta Often Used to Treat Symptoms of Parkinson’s and Dementia Off-label, Study Finds

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An oral medicine approved to treat pseudobulbar affect — involuntary outbursts of laughing or crying — in people with amyotrophic lateral sclerosis or multiple sclerosis is most often prescribed to treat those ... Read more

January 11, 2019January 17, 2019

Abnormal Brain Cell Type Leads to Parkinson’s-Related Neurodegeneration, Study Contends

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Scientists have found that an abnormal version of brain cells called astrocytes contribute to the accumulation of alpha-synuclein protein, the main component of Parkinson’s disease hallmark Lewy bodies. Their ... Read more

January 11, 2019January 11, 2019

Genetic Variant Predetermines Risk of Cognitive Decline in Parkinson’s, Research Suggests

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Researchers have found that Parkinson’s patients whose cognitive ability is intact, but who have a specific genetic variant, have significantly less gray matter in the regions of their brain that are ... Read more

January 10, 2019January 21, 2019

Changes in Gait, Cognition May Be Early Signs of Idiopathic Parkinson’s, Research Suggests

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Changes in gait and cognition precede a diagnosis of idiopathic (without known cause) Parkinson’s disease, and may occur earlier than typical non-motor symptoms, a study has found. The study, “Prediagnostic markers of idiopathic ... Read more

January 10, 2019January 15, 2019

Inbrija Approved in US to Treat Off Periods in Parkinson’s Patients on Carbidopa/Levodopa

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The U.S. Food and Drug Administration has approved Inbrija (levodopa inhalation powder)‎ for the treatment of Parkinson’s off periods in patients on a carbidopa/levodopa regimen. Acorda Therapeutics’ therapy is ... Read more

January 9, 2019January 16, 2019

Phase 2 Trial of Gene Therapy VY-AADC to Include More Parkinson’s Patients

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The ongoing Phase 2 study of the gene therapy VY-AADC will enroll more Parkinson’s disease patients than originally planned, Voyager Therapeutics announced. The company’s revised trial protocol will include more ... Read more

January 9, 2019January 9, 2019

Gout May Increase Parkinson’s Risk in Older People, Study of US Medicare Data Suggests

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Gout appears to be associated with a higher risk of incident Parkinson’s disease in older adults, according to a study that looked at Medicare data in the U.S. The ... Read more

January 8, 2019January 8, 2019

Researchers Evaluate Computer-based Therapy to Ease Fatigue, Improve Motor Function

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An ongoing pilot trial is evaluating a computer-based, non-pharmacological cognitive approach to improve motor function and ease fatigue in people with Parkinson’s disease. “Study protocol for a randomised pilot study ... Read more

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